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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd9211a41e5495326868b5bb2f973a3f1116473e4a1e0267aefc53b66caf67f' 
  AND token = 'a+jHnCQC5qOm3UkT1THjNTlCWlQ6sB3QuPkU2TZFLiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}