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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d84d4f18ac0aecae0c9f5bb59303040d8ff2eb087dbe0af7c50527476a1bc49' 
  AND token = 'uKuhsGsB2zuQf1F4/hEvPQ4YFXFstp6mX2MqCcYkoOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}