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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d423b2b543dd3fcdfcd1f84e7270a02a566d38f37906f79adfc7159d49faa6b' 
  AND token = 'U5XtAHLxgC+r7uYopFq8wjwHkganhYnqXFC9y3CEoa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}