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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d0aae40c7b167a3bcbc257f99707925c0910c213a5f0fba4bc5384e7769284' 
  AND token = 'P8Uvrr45kKj9+DzWko0zljq3WkHHoiPKxVxp1XaCSIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}