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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d6a7dbda25bf203198632c36812b2b472b41b95f6f80f0347f3fb777ad4c25' 
  AND token = 'eqXnxvEqKLuXLLg719P+bL7Uev6WWNJYExP4+Ylzv0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}