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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99346868181b4f4d094e41cdcc8c29472a9b43ce16dd80c990842d6f3d33641b' 
  AND token = 'g/TkeFSbp3wzZLh+LnskWo93cDms2Bl0URSfi+GYe5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}