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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80504b2a4058bf3bdce922ccf135f062a4e7d218a560c171584ab7df167e7fab' 
  AND token = 'tm99C+zYySfVnRip+zG1+bXwrwn4kfp+60fZZRHf4E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}