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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6c6fd8ae640cf8b08e1d079fc7fe51fe4203841e92d3c3dc975923d1465111e' 
  AND token = '6mn6S+vKmkKHqcs2BC8Vqyp4fCCxKpS/Hsl2LZ9XrzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}