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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ecb3aacf99cd1fc455902ab308b6abba7853b5be3a06b39549012e5719f1d6a' 
  AND token = '5CxeZtARR9SYm6ASATKszsjCF0/K0jaLQ8bG/Yq6B+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}