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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b402502376dc160ef12864fa74517f550f5c611b34d321f7265a525d4165171f' 
  AND token = 'FRjp6qZE/UiIMdRO1darIb3+iF+AY8lAXnDnqSQQZb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}