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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a23b7e77ca03e90b1e42f7828cfd3bdd54ae5e378d7ca1d72fde5955b5636f66' 
  AND token = 'EffMqpx85Papl3b3o4XClAP6dSCLU4kq0BPeleFh9bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}