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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52199590334b0781bd4f92be9b4e7f5b5a2ffa90936ef2706c05751b02be2f3b' 
  AND token = 'zhcfKsjgKsXGkrXgt/vrRcNHS/XtTy3duCAsDJ7gr3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}