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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7247104363d8c903c7f827a0a14ca84e76b63496ae424d41604294d246973091' 
  AND token = 'U1vrHs6FWRQqj4nhtOkYr4+baUYSuu6Xbd1xj2rx2qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}