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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28a846fc2442efa096b1bb72d42710722bbd379227ffcc847eeefae20abdb1a4' 
  AND token = 'jZK/34DrJqXYyg4jdZk7G/5xVIyVxxC7dG4D+3mu330=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}