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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67d9dc841e9e556d6a76b64759759e377eb49ee6a013b58d9abb428d4d62476d' 
  AND token = '7N+v7XZau5wZr128wB1UbNizswsmkGeWV3Slwsm2q+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}