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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78148e65e8bffe6cbaa9b1fed52e75e1a486ef3bad798db061f87e5e71f81c5' 
  AND token = '7EsRp4Op5JEqgZmB71DZlXX7RgIS3+ZOvisazDxw1xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}