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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af918d84925db32255cc20bd54952df2afea121c466fd622fcf19d2da82dcbd2' 
  AND token = 'nbbYdxiwVFvTKnznfM70yjnnKnvp5Z+Q7zI++WP3gQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}