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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50a6bf852626fa73e4c1e7e7c21410f240c4b42d0318288507ffb661898b8c6' 
  AND token = 'lQgnTNeiTLQHAgW4/dfmdQgv4TYLZevlL1MoY4FkmUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00427

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}