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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dff92dbf16538b96a362985260f5e48367b691b6b0cad260ade5a359f6ab55a' 
  AND token = '+NIOoftqTGO9nKFTXKzKGP288uOdJwRnPB8VJnyauGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}