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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a7891fba8a061c70ff9b360227d4554c05d4900b89ebcdcb6dccb25ce6e6252' 
  AND token = 'dxepBqnneW5hNt1UXPPynZ7GKHQx3QPDEtfVuV+BEQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}