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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5f03b51bc99d45061d25533bbba7e8f497520db3d4028da9cd5431c5543dbd' 
  AND token = 'MBTFm5YaAULeuXgDdjTLnFAQU+z9pBlLBgGc1d8GVOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}