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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ab22e145a239c1384260bd17c6c817ae2f9d7c493f3c22800f8b78920878535' 
  AND token = 'cZCr1ppu+Z6oej9JMjEl225zFVWq6nzPSN74ohp8AKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}