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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f295ee9067fbf27254f6dfc65dd21d9743eea2de654ad66985eb7fded7dd7c9' 
  AND token = 'GPUGFicIxLEflkCo2mW18feiw6DJTyjodfbY/T84S0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}