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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5e087e8c41d1729799fb91af7c319f351067b10251e71a0a01546ce1b4e8b8a' 
  AND token = 'rKCTG1+PoLD03GaY/ju7vT4xFg0rifhvY+lokzJ0Qp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00284

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}