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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b892f0f7481b35e90718359d9c166e454d07828e9c8f04d0f3b0726bb22a9215' 
  AND token = 'CQC8bKAgk8sdjbxHiLTV9DeA+GpeoR4hSUrz7UUThyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}