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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c45565226c672c58e11504b2a959734bea44c73e4177fc2086029ee2fe378003' 
  AND token = 'PYkQYsSJw7AI3K5RIJRRHQLVopJVv5Wd2gMG6fJWOtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}