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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11050395a26a2e8eeb193d704d98b3a6e3e4c4fb115a64ad84a3a51f512b1c8f' 
  AND token = 'ro+kCfa+M8YtcaNR0n+vtwgt9gv1zAIvkXpBZI8sZGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}