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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9053a98d422866759068b6c81a5a74eca74fec02c4a75c8768beca683b5b1ea' 
  AND token = '4hQdQ0/ArjKTFEjI+8RCbjsv2ygFc/BmTOlEPEh9mhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}