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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cadda2e1d5f3220befafdcc9335a3fe98a53b647086247322005a5a90130515' 
  AND token = 'nq99vX/jbzKuuj7cfL8aNbaj+jaES2zhyOZVev6xy18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}