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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8686d89489b102be13667ff6f0ad1f2ea0ef09c558682d968980dfeac9c2e4d' 
  AND token = 'w9rp/awT28gE3c0nci3O+ipfc1lyFf6HSNj9LDmrkFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}