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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5885330593600c3042a48c660d4b36cc5de74e0c869ebaf9fb88813aa886637f' 
  AND token = 'bMVwJ3zgTaE4bJXgiUkL5wJtmDDveBu9LNAOYK8sZKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}