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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57ac59c5855d8aee94f36ea380849f6dc79bdc24195778fc5c0e76c2ad516733' 
  AND token = 'jedrAGm2+uaAW69fv3ShrTxLGKAp/Jfmxf3Yb5dtIxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}