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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9485d0a6d90d3d6251ba6e795af450ea80076651cbe70a4b2c3eedf8357024' 
  AND token = 'bpI+QUJ4pcY9qMLY9zVqKS36iPqFXqkzLXXo/n2dKs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}