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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10f3a6e988f09f34e901eb588d3d112eada12c33298a41ff48f252cbaa493fb' 
  AND token = 'EO+Q76NVZjtxbwezgct+TWhCzZYe7wpVNyB2MQ0BBOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}