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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4812e07716e120913c3af359b0d4bca6ca87c17a34e08342c435bc80f40831d3' 
  AND token = '+7b+odSn566no6lzlpOtz990zZB6vvRNxdjmlRNSz+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}