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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '447866f55ade907711da7077e71c483b17da012ebe52aa20a1fc77118759d104' 
  AND token = 'eXTeowT9GQ7Dyz9JNG8nYy7O0axcyzYf/f20UXydv/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}