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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5cb64728344106fa3044d2907d3c638f6810953a33bee60a1bb7aa436065a0' 
  AND token = '08wa9I8PW6tVg5EkCzOTgHW+aVug3OE7TydWz9Rg93Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}