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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455afb90ff921125cbd9c7376b9a16fa1431aeede9d37b8c5a4aca0a2073f0bd' 
  AND token = 'Liif1DI5/LcjpkFklGp198UVRJlQvYnwgweH7Tx49wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}