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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf3cb24f543f6d3e4a1fcd8d9af432461503b8aa2f174771605debcc27ae78a' 
  AND token = 'A4Oy5GK/rouTmWXe9LkEaEDfqU2DbCIBH+FZTZk5/F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}