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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc727837d3efa99f2171e18e2ce17a5054eaa169adbf05c6cfc5857f90b426df' 
  AND token = 'WVV9b0eHoQtraG5nFdou/oWwSfokl8xYD9WjXMH21hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}