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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53fada104fe99820d4b585d0175b59e8927030e64667b259340c05d00c901e93' 
  AND token = '6wrgsqhhvEJI/JiImCWT6NYyVrBImDsH6icKaq7HeIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}