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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1159b01e7df5acebbb7ba698b1720367d81c7c6c5bd54e1111db31eea3e2e8fa' 
  AND token = 'qUNzUOLrwzsg+CyckIFtmtlYqODp6Mu+iM3B5xC4KQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}