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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c62ae04b675bbd5b4dc3c21c0aff925cf0053211a8d788898bc4daef4e290d5' 
  AND token = 'Khaca33pzJZ9vYtJsNv44cHd4fad7cLnu87fhtexL9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}