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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9a7b0f304f2ec3746c159f93abdf6abfaebee6ed83e98189641824959c16af' 
  AND token = 'EAhA63I/nQCjQprimwIa18FxjDw04g1AMkFD/E3EyaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}