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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a6ae58ea9b3b85ef8674932e6526f2f8186dcd742e56867ecc5c6ebee96680' 
  AND token = 'ZHS7Wp4dHkNB4tdSo+NwvH0uU0UQK91kCHIORP6nmh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}