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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6da530c555d068c7b6ef6574e9d2fe0e04df1aa3a87997b7d78d469be96acf5e' 
  AND token = 'd4bIj8w3Dg7hedz0ltvUjAdXDiaa0pSzAwXK7oDCDj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}