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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23b9d30f2d57a7744819ab50a5665da8a36ac68f7e268f91615e2f67c20a2ceb' 
  AND token = 'Iq9UPc6Ukj+RdO8+nUP0neMQhALkc4NT17wbjXsBIIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}