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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '480b4bfba997903c302c32337a9543e01ca9d5b0b349da152b1d0cf1b0bf1f58' 
  AND token = 'gg+CDsFpMf5cnSuy5ep49FE6S/OmcU8h1uBn0S97J88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}