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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcb7033e8ea5cfa900b6067ceb38d63894e65a1c4b24340e6a8206f3be88be91' 
  AND token = 'Fv+zD/WzPUqh6zgzwcBD7W7LK9oyTXhHRSeb34MFCaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}