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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9c4bc07a34e87e9578788375a5b5aacca646e57b6d3c2233c8b6970f9b26dd' 
  AND token = 'Za6yCsCd5AxjSNEVR5ATQe/betc8WGKXt3EFiZ3FJE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}